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  5. Tocris Bioscience™ N-Acetylcysteine amide

Tocris Bioscience™ N-Acetylcysteine amide
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Catalog No. 561910
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Description

Glutathione (GSH) precursor; neuroprotective

N-Acetylcysteine amide is a glutathione (GSH) precursor and cell-permeable antioxidant. N-Acetylcysteine amide replenishes intracellular Glutathione (GSH). N-Acetylcysteine amide directly reduces intracellular Glutathione disulfide (GSSG) to GSH without glutathione peroxidase. N-Acetylcysteine amide has anti-inflammatory activity through regulation of activation of NF-κB and HIF-1α, as well as modulation of reactive oxygen species. N-Acetylcysteine amide improves neuronal mitochondrial bioenergetics, reduces tissue damage and enhances functional recovery following spinal cord injury in rats. N-Acetylcysteine amide also enhances behavioral recovery in rats following traumatic brain injury. Neuroprotective.

For more information about how N-Acetylcysteine amide may be used, see our protocol: 3D Culture of Lung Alveolar Cells

Specifications

Chemical Name or Material (2R)-2-(Acetylamino)-3-mercaptopropanamide
CAS 38520-57-9
Quantity 10 mg
Target Additional Antioxidant Compounds
Molecular Formula C5H10N2O2S
Formula Weight 162.21
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