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Invitrogen™ n-Myc Polyclonal Antibody
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Catalog No. PIPA5105270
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100 μL
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PIPA5105270 100 μL
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Catalog No. PIPA5105270 Supplier Invitrogen™ Supplier No. PA5105270
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total n-Myc.

N-Myc protein is member of the MYC family of transcription factor proteins with a basic helix-loop-helix (bHLH) domain. N-Myc is similarly regulated and functionally complementary to C-Myc in the context of various cellular growth and differentiation processes. MYCN gene is considered the hallmark of neuroblastoma, amplification and overexpression of the MYCN proto-oncogene occurs in approximately 20% of neuroblastomas and is associated with advanced stage disease, rapid tumor progression, and poor prognosis.
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Specifications

Antigen n-Myc
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene MYCN
Gene Accession No. P03966, P04198, Q63379
Gene Alias Avian myelocytomatosis viral (v-myc) related oncogene neuroblastoma derived (Nmyc); Avian myelocytomatosis viral (v-myc) related oncogene, neuroblastoma derived (Nmyc); BHLHE37; Class E basic helix-loop-helix protein 37; c-nmyc; fb57a02; MODED; Mycn; mycn protein; MYCN proto-oncogene, bHLH transcription factor; neuroblastoma MYC oncogene; neuroblastoma myc-related oncogene 1; neuroblastoma-derived v-myc avian myelocytomatosis viral related oncogene; Nmuc1; NMYC; N-myc; N-myc protein; N-myc proto-oncogene protein; Nmyc1; Nmyc-1; N-myc-like protein; ODED; oncogene NMYC; oncogene pp65/67; pp65/67; v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog; v-myc myelocytomatosis viral related oncogene, neuroblastoma derived; v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian); wu:fb57a02; zgc:85706
Gene Symbols MYCN
Host Species Rabbit
Immunogen A synthesized peptide derived from human MYCN(Accession P04198), corresponding to amino acid residues A235-R285.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18109, 298894, 4613
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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