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N-Myc Polyclonal Antibody, Active Motif™
SDP

Catalog No. 501993214
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50-199-3214 100 μL
50-199-3215 10 μL
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Catalog No. 50-199-3214 Supplier Active Motif Supplier No. 61185
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Description

Rabbit Polyclonal Antibody

N-Myc protein is member of the MYC family of transcription factor proteins with a basic helix-loop-helix (bHLH) domain. N-Myc is similarly regulated and functionally complementary to C-Myc in the context of various cellular growth and differentiation processes. MYCN gene is considered the hallmark of neuroblastoma, amplification and overexpression of the MYCN proto-oncogene occurs in approximately 20% of neuroblastomas and is associated with advanced stage disease, rapid tumor progression, and poor prognosis.

Specifications

Antigen N-Myc
Applications ChIP sequencing (ChIP-seq), Western Blot
Classification Polyclonal
Concentration Lot-Specific
Conjugate Unconjugated
Formulation 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene MYCN
Gene Accession No. P04198
Gene Alias Avian myelocytomatosis viral (v-myc) related oncogene neuroblastoma derived (Nmyc); Avian myelocytomatosis viral (v-myc) related oncogene, neuroblastoma derived (Nmyc); BHLHE37; Class E basic helix-loop-helix protein 37; c-nmyc; MODED; Mycn; neuroblastoma MYC oncogene; neuroblastoma myc-related oncogene 1; neuroblastoma-derived v-myc avian myelocytomatosis viral related oncogene; Nmuc1; Nmyc; N-myc; N-myc proto-oncogene protein; Nmyc1; Nmyc-1; ODED; oncogene NMYC; oncogene pp65/67; pp65/67; v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog; v-myc myelocytomatosis viral related oncogene, neuroblastoma derived; v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
Gene Symbols MYCN
Host Species Rabbit
Immunogen This N-Myc antibody was raised against a peptide derived from the C-terminal region of human N-Myc.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4613
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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