Invitrogen™ N-Ras Monoclonal Antibody (06)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA529452

Catalog No. PIMA529452

Description

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human NRAS/N-Ras.

NRAS (GTPase NRas) is a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. This protein, which has intrinsic GTPase activity, is activated to a GTP-bound form by a GTPase activating protein and inactivated to a GDP-bound form by a guanine nucleotide-exchange factor. Defects in the gene encoding this protein are a cause of juvenile myelomonocytic leukemia (JMML) and Noonan syndrome 6.

Specifications

• Antigen: N-Ras
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: P01111
• Gene Symbols: NRAS
• Immunogen: Recombinant Human NRAS/N-Ras Protein (Met1-Cys186).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Western Blot
• Clone: 06
• Conjugate: Unconjugated
• Gene: NRAS
• Gene Alias: ALPS4; AV095280; CMNS; GTPase NRas; HRAS1; NCMS; Neuroblastoma RAS; neuroblastoma ras oncogene; neuroblastoma RAS viral (v-ras) oncogene homolog; neuroblastoma RAS viral oncogene homolog; Nras; N-ras; N-ras protein part 4; NRAS1; NS6; RAS; RASN; transforming protein N-Ras; v-ras neuroblastoma RAS viral oncogene homolog
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 4893
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid