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Invitrogen™ N-Ras Polyclonal Antibody
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Catalog No. PIPA528861
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100 μL
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PIPA528861 100 μL
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Catalog No. PIPA528861 Supplier Invitrogen™ Supplier No. PA528861
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: mouse brain. Predicted reactivity: Mouse (99%), Rat (99%), Zebrafish (90%), Xenopus laevis (92%), Dog (100%), Pig (100%), Chicken (96%), Bovine (100%), Guinea pig (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

NRAS (GTPase NRas) is a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. This protein, which has intrinsic GTPase activity, is activated to a GTP-bound form by a GTPase activating protein and inactivated to a GDP-bound form by a guanine nucleotide-exchange factor. Defects in the gene encoding this protein are a cause of juvenile myelomonocytic leukemia (JMML) and Noonan syndrome 6.
TRUSTED_SUSTAINABILITY

Specifications

Antigen N-Ras
Applications Western Blot
Classification Polyclonal
Concentration 0.41 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene NRAS
Gene Accession No. P01111, P08556, Q04970
Gene Alias ALPS4; AV095280; CMNS; GTPase NRas; HRAS1; NCMS; Neuroblastoma RAS; neuroblastoma ras oncogene; neuroblastoma RAS viral (v-ras) oncogene homolog; neuroblastoma RAS viral oncogene homolog; Nras; N-ras; N-ras protein part 4; NRAS1; NS6; RAS; RASN; transforming protein N-Ras; v-ras neuroblastoma RAS viral oncogene homolog
Gene Symbols NRAS
Host Species Rabbit
Immunogen Full length human N-Ras Recombinant protein.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18176, 24605, 4893
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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