Invitrogen™ N-Ras Polyclonal Antibody

Catalog No.	Quantity
PIPA514833	400 μL

Catalog No. PIPA514833 Supplier Invitrogen™ Supplier No. PA514833

Description

Rabbit Polyclonal Antibody

This antibody is predicted to react with porcine based on sequence homology.

NRAS (GTPase NRas) is a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. This protein, which has intrinsic GTPase activity, is activated to a GTP-bound form by a GTPase activating protein and inactivated to a GDP-bound form by a guanine nucleotide-exchange factor. Defects in the gene encoding this protein are a cause of juvenile myelomonocytic leukemia (JMML) and Noonan syndrome 6.

Specifications

• Antigen: N-Ras
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene: NRAS
• Gene Accession No.: P01111
• Gene Alias: ALPS4; AV095280; CMNS; GTPase NRas; HRAS1; NCMS; Neuroblastoma RAS; neuroblastoma ras oncogene; neuroblastoma RAS viral (v-ras) oncogene homolog; neuroblastoma RAS viral oncogene homolog; Nras; N-ras; N-ras protein part 4; NRAS1; NS6; RAS; RASN; transforming protein N-Ras; v-ras neuroblastoma RAS viral oncogene homolog
• Gene Symbols: NRAS
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide between 147-179 amino acids from the C-terminal region of human NRAS.
• Purification Method: Size-exclusion - Dialysis, Ammonium sulfate precipitation
• Quantity: 400 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4893
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG