Invitrogen™ N-terminal Arginylation Monoclonal Antibody (4A9), APC

Catalog No.	Quantity
PIMA545370	100 μg

Catalog No. PIMA545370

Supplier: Invitrogen™ MA545370

Description

Mouse Monoclonal Antibody

A 1:1,000 dilution of MA5-45370 was sufficient for detection of N-terminal Arginylation in 0.5 μg of N-terminal Arginine peptide conjugated to BSA by ECL immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody. Specific for N-terminal arginine next to glutamic acid. Does not detect N-terminal arginine next to aspartic acid or internal arginine residues.

Protein arginylation is the post-translational addition of arginine to proteins by arginyltransferase ATE1. Arginylation of proteins has been found to play an essential role in physiological pathways during embryogenesis and adulthood. Arginylation has also been shown to regulate cell stress responses, including ER stress, cytosolic misfolded proteins, and heat stress.

Specifications

• Antigen: N-terminal Arginylation
• Applications: Flow Cytometry, Western Blot
• Classification: Monoclonal
• Clone: 4A9
• Concentration: 1 mg/mL
• Conjugate: APC
• Formulation: 2.48mM MES, 95.64mM phosphate with 0.5M EDTA and no preservative; pH 7.4
• Gene Alias: N terminal Arginine; N-terminal Arginine
• Host Species: Mouse
• Immunogen: Synthetic N-terminal arginylated peptide conjugated to KLH.
• Purification Method: Protein G
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Chemical
• Content And Storage: 4°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1
• Target Molecule: Chemical