Invitrogen™ N-terminal Arginylation Monoclonal Antibody (4A9)

Catalog No.	Quantity
PIMA527563	100 μg

Catalog No. PIMA527563 Supplier Invitrogen™ Supplier No. MA527563

Description

Mouse Monoclonal Antibody

MA5-27563 is specific for N-terminal arginine next to glutamic acid. It does not detect N-terminal arginine next to aspartic acid or internal arginine residues. A 1:1,000 dilution of MA5-27563 was sufficient for detection of N-terminal Arginylation in 0.5 μg of N-terminal Arginine peptide conjugated to BSA by ECL immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody. Specific for N-terminal arginine next to glutamic acid. Does not detect N-terminal arginine next to aspartic acid or internal arginine residues.

Protein arginylation is the post-translational addition of arginine to proteins by arginyltransferase ATE1. Arginylation of proteins has been found to play an essential role in physiological pathways during embryogenesis and adulthood. Arginylation has also been shown to regulate cell stress responses, including ER stress, cytosolic misfolded proteins, and heat stress.

Specifications

• Antigen: N-terminal Arginylation
• Applications: Flow Cytometry, Western Blot
• Classification: Monoclonal
• Clone: 4A9
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
• Gene Alias: Arginyltransferase; Arginyltransferase 2; Arginyl-tRNA--protein transferase; Arginyl-tRNA--protein transferase 2; arg-tRNA-protein transferase; arg-tRNA-protein transferase 2; ATE1; ATE2; N terminal Arginine; N-terminal Arginine; R-transferase; R-transferase 2
• Host Species: Mouse
• Immunogen: Synthetic N-terminal arginylated peptide conjugated to KLH.
• Purification Method: Protein G
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Chemical
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1
• Target Molecule: Chemical