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Invitrogen™ N-WASP Monoclonal Antibody (C.427.3)
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Catalog No. PIMA515011
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100 μL
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Catalog No. Quantity
PIMA515011 100 μL
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Catalog No. PIMA515011 Supplier Invitrogen™ Supplier No. MA515011
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Description

Rabbit Monoclonal Antibody

It is not recommended to aliquot this antibody.

The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. The WASL gene product is a homolog of WAS protein, however, unlike the latter, it is ubiquitously expressed and shows highest expression in neural tissues. It has been shown to bind Cdc42 directly, and induce formation of long actin microspikes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen N-WASP
Applications Immunoprecipitation, Western Blot
Classification Monoclonal
Clone C.427.3
Concentration 8 μg/mL
Conjugate Unconjugated
Formulation 0.01M HEPES with 100 μg/mL BSA, 50% glycerol, 0.15M NaCl and <0.02% sodium azide; pH 7.5
Gene WASL
Gene Accession No. O00401, O08816, Q91YD9, Q95107
Gene Alias 2900021I12Rik; 3110031I02Rik; DKFZp779G0847; MGC48327; n wasp; neural Wiskott-Aldrich syndrome protein; NWASP; N-WASP; TRS4; WASL; WASP like actin nucleation promoting factor; WASPB; Wiskott-Aldrich syndrome like; Wiskott-Aldrich syndrome-like; Wiskott-Aldrich syndrome-like (human)
Gene Symbols WASL
Host Species Rabbit
Immunogen Synthetic peptide corresponding the sequence of human N-WASP.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100757697, 281577, 682507, 73178, 8976
Target Species Human, Mouse, Rat, Monkey, Bovine, Hamster
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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