Invitrogen™ N-WASP Recombinant Rabbit Monoclonal Antibody (K01_1W05)

Rabbit Recombinant Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
MA563474	Invitrogen™ MA563474	100 μL
MA564933	Invitrogen™ MA564933	50 μL

Description

N-WASP Recombinant Monoclonal Antibody for ICC/IF, IHC (P), Western Blot

The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. The WASL gene product is a homolog of WAS protein, however, unlike the latter, it is ubiquitously expressed and shows highest expression in neural tissues. It has been shown to bind Cdc42 directly, and induce formation of long actin microspikes.

Specifications

• Antigen: N-WASP
• Concentration: 1 mg/mL
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: 50mM tris glycine with 40% glycerol, 0.05% BSA, 150mM NaCl and 0.01% sodium azide; pH 7.4
• Gene Accession No.: O00401, Q91YD9
• Gene ID (Entrez): 73178, 8976
• Immunogen: A synthetic peptide of human N-WASP.
• Product Type: Antibody

• Clone: K01_1W05
• Content And Storage: Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
• Classification: Recombinant Monoclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Human, Mouse
• Gene: WASL
• Gene Alias: 2900021I12Rik; 3110031I02Rik; DKFZp779G0847; MGC48327; n wasp; neural Wiskott-Aldrich syndrome protein; NWASP; N-WASP; TRS4; WASL; WASP like actin nucleation promoting factor; WASPB; Wiskott-Aldrich syndrome like; Wiskott-Aldrich syndrome-like; Wiskott-Aldrich syndrome-like (human)
• Gene Symbols: WASL
• Primary or Secondary: Primary
• Purification Method: Protein A/G