Invitrogen™ N2DL4 Monoclonal Antibody (709116)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA524328

Catalog No. PIMA524328

Description

In Western blots, approximately 20% cross-reactivity with recombinant human (rh) ULBP-2 is observed and no cross-reactivity with rhULBP-1 or rhULBP-3 is observed. Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.

This gene belong to the RAET1 family, which consists of major histocompatibility complex (MHC) class I-related genes located in a cluster on chromosome 6q24.2-q25.3. This and RAET1G protein differ from other RAET1 proteins in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol anchor sequences. This protein functions as a ligand for NKG2D receptor, which is expressed on the surface of several types of immune cells, and is involved in innate and adaptive immune responses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2011].

Specifications

• Antigen: N2DL4
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q8TD07
• Gene Symbols: RAET1E
• Immunogen: Mouse myeloma cell line NS0-derived recombinant human ULBP-4/RAET1E Gly30-Asp225.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Clone: 709116
• Conjugate: Unconjugated
• Gene: RAET1E
• Gene Alias: bA350J20.7; LETAL; Lymphocyte effector toxicity activation ligand; MGC125309; N2DL4; N2DL-4; NKG2D ligand 4; NKG2DL4; Rae-1 epsilon; RAE1 like transcript 4; RAE1epsilon; RAE-1-epsilon; RAE-1-like transcript 4; RAET1E; RAET1E2; Retinoic acid early transcript 1E; retinoic acid early-inducible protein 1-epsilon; RL-4; UL16 binding protein 4; UL16-binding protein 4; ULBP 4; ULBP4; ULBP4MGC125308; UNQ1867/PRO4303
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 135250
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized