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Invitrogen™ N4BP1 Polyclonal Antibody
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Catalog No. PIPA5101701
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100 μL
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PIPA5101701 100 μL
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Catalog No. PIPA5101701 Supplier Invitrogen™ Supplier No. PA5101701
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total N4BP1.

Nedd4-binding partner-1 (N4BP1) is a developmentally expressed protein interactor and monoubiquitylation substrate of Nedd4, a HECT domain-containing ubiquitin ligase that mediates ubiquitylation and proteasome degradation of target proteins and may have a fundamental role to play in embryonic processes. N4BP1 can undergo Nedd4-mediated polyubiquitylation and proteosomal degradation. N4BP1 also functions as a negative regulator of AIF4 (also known as ITCH or Atrophin-1), an E3-ubiquitin ligase, by interacting with the second WW domain of AIF4 and impairing ubiquitination of substrates.
TRUSTED_SUSTAINABILITY

Specifications

Antigen N4BP1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene N4BP1
Gene Accession No. O75113
Gene Alias AI481586; C81621; Kiaa0615; N4BP1; Nedd4 binding protein 1; NEDD4-binding protein 1; RGD1305179
Gene Symbols N4BP1
Host Species Rabbit
Immunogen A synthesized peptide derived from human N4BP1(Accession O75113), corresponding to amino acid residues E382-A432.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9683
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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