Invitrogen™ N4BP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA521099

Catalog No. PIPA521099

Description

A suggested positive control is Hela cell lysate. PA5-21099 can be used with blocking peptide PEP-1213.

Nedd4-binding partner-1 (N4BP1) is a developmentally expressed protein interactor and monoubiquitylation substrate of Nedd4, a HECT domain-containing ubiquitin ligase that mediates ubiquitylation and proteasome degradation of target proteins and may have a fundamental role to play in embryonic processes. N4BP1 can undergo Nedd4-mediated polyubiquitylation and proteosomal degradation. N4BP1 also functions as a negative regulator of AIF4 (also known as ITCH or Atrophin-1), an E3-ubiquitin ligase, by interacting with the second WW domain of AIF4 and impairing ubiquitination of substrates.

Specifications

• Antigen: N4BP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: N4BP1
• Gene Alias: AI481586; C81621; Kiaa0615; N4BP1; Nedd4 binding protein 1; NEDD4-binding protein 1; RGD1305179
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 291921, 80750, 9683
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: O75113, Q6A037
• Gene Symbols: N4BP1
• Immunogen: An 18 amino acid peptide near the amino terminus of human N4BP1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG