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Invitrogen™ N4BP1 Polyclonal Antibody
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Catalog No. PIPA5117135
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PIPA5117135 100 μL
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Catalog No. PIPA5117135 Supplier Invitrogen™ Supplier No. PA5117135
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Rabbit Polyclonal Antibody

Positive Samples: Jurkat, 293T, Mouse brain, Mouse pancreas Immunogen sequence: TQGEESLFET DDDVITVGDV RPPEYTQSAA TGPSSARDEV VVQEDSRNKA RTPVSELTKH MDTVFSSSPD VLFVPVNGLS PDEDALSKDR VCHKRRSSDT EERHTKKQFS LENVPEGELL PDGKGSAGNE VIDLSDPASN STNLSPDGKD TTEEMEYNIL VNFFKTMGYS QEIVEKVIRE YGPSTEPLLL LEEIEKENKR LQEDRDFPPC TVYPDASQSR NAGVGSTTNE LTADSTPKKA QSHTEQSMVE RFSQLPFKDS KHCTSNCKVN SFRTVPVGQK QEIWGSKQNS SCTVDLETDG HSASAASASP KDISFVSRGA SGHQQRNPAF PENGFQQQTE PLLPNNTKPA CEKRSGSCSS PQPKPNYPPL SPPLPLPQLL PSVTEARLGG SSDHIDSSVT G.

Nedd4-binding partner-1 (N4BP1) is a developmentally expressed protein interactor and monoubiquitylation substrate of Nedd4, a HECT domain-containing ubiquitin ligase that mediates ubiquitylation and proteasome degradation of target proteins and may have a fundamental role to play in embryonic processes. N4BP1 can undergo Nedd4-mediated polyubiquitylation and proteosomal degradation. N4BP1 also functions as a negative regulator of AIF4 (also known as ITCH or Atrophin-1), an E3-ubiquitin ligase, by interacting with the second WW domain of AIF4 and impairing ubiquitination of substrates.
TRUSTED_SUSTAINABILITY

Specifications

Antigen N4BP1
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.91 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide; pH 7.3
Gene N4BP1
Gene Accession No. O75113, Q6A037
Gene Alias AI481586; C81621; Kiaa0615; N4BP1; Nedd4 binding protein 1; NEDD4-binding protein 1; RGD1305179
Gene Symbols N4BP1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 190-590 of mouse N4BP1 (NP_0850402).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 80750, 9683
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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