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Invitrogen™ NAE1 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5100385

Catalog No. PIPA5100385


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Description

Description

Antibody detects endogenous levels of total APPBP1.

The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

NAE1
Polyclonal
Unconjugated
NAE1
59kDa; A-116A10.1; amyloid beta precursor protein binding protein 1, 59kDa; amyloid beta precursor protein-binding protein 1, 59 kDa; amyloid beta precursor protein-binding protein 1, 59kD; amyloid protein-binding protein 1; Appbp1; APP-BP1; HPP1; Nae1; NEDD8 activating enzyme E1 subunit 1; NEDD8-activating enzyme E1 regulatory subunit; NEDD8-activating enzyme E1 subunit; protooncogene protein 1; proto-oncogene protein 1; ula-1
Rabbit
Affinity chromatography
RUO
234664, 84019, 8883
-20°C
Liquid
Western Blot
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Q13564, Q8VBW6, Q9Z1A5
NAE1
A synthesized peptide derived from human NAE1(Accession Q13564), corresponding to amino acid residues K83-E133.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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