Invitrogen™ NAE1 Monoclonal Antibody (OTI1E10)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA526665

Catalog No. PIMA526665

Description

NAE1 Monoclonal Antibody for Western Blot, IHC (P)

The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: NAE1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q13564
• Gene Symbols: NAE1
• Immunogen: Human recombinant protein fragment corresponding to amino acids 1-274 of NAE1 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI1E10
• Conjugate: Unconjugated
• Gene: NAE1
• Gene Alias: 59kDa; A-116A10.1; amyloid beta precursor protein binding protein 1, 59kDa; amyloid beta precursor protein-binding protein 1, 59 kDa; amyloid beta precursor protein-binding protein 1, 59kD; amyloid protein-binding protein 1; Appbp1; APP-BP1; HPP1; Nae1; NEDD8 activating enzyme E1 subunit 1; NEDD8-activating enzyme E1 regulatory subunit; NEDD8-activating enzyme E1 subunit; protooncogene protein 1; proto-oncogene protein 1; ula-1
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8883
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid