NAE1 Mouse anti-Human, Clone: OTI1E10, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA526665
DescriptionThe protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer ft.s disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|HPP1; ula-1; NAE1; A-116A10.1; NEDD8-activating enzyme E1 regulatory subunit; Amyloid protein-binding protein 1;Amyloid beta precursor protein-binding protein 1, 59 kDa; Proto-oncogene protein 1|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Human recombit protein fragment corresponding to amino acids 1-274 of NAE1 produced in E.coli|
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