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Invitrogen™ NAGA Polyclonal Antibody
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Catalog No. PIPA597299
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PIPA597299 100 μL
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Catalog No. PIPA597299 Supplier Invitrogen™ Supplier No. PA597299
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Description

Rabbit Polyclonal Antibody

Positive Samples: HL-60, Mouse liver, Mouse kidney, Mouse lung, Rat testis; Cellular Location: Lysosome.

NAGA (N-acetylgalactosaminidase, alpha), also known as alpha-galactosidase B or GALB, is a 411 lysosomal protein belonging to the glycosyl hydrolase 27 family that may exist as a homodimer and plays a critical role in glycolipid breakdown. NAGA encodes alpha-N-acetylgalactosaminidase, a lysosomal enzyme, which cleaves alpha-N-acetylgalactosaminyl groups from glycoconjugates. Mapping to human chromosome 22q13. 2, NAGA defects are the cause of an autosomal recessive disorder with three phenotypes, known as Schindler disease (types I, II and III) or NAGA deficiency (types I, II and III). Characterized by neurologic manifestations that range in severity, Schindler disease type I is the most severe form, followed by type III, which may have mild-to-moderate effects. Schindler disease type II, also known as Kanzaki disease, is characterized by mild intellectual impairment and angiokeratoma corporis diffusum.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NAGA
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.99 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene NAGA
Gene Accession No. P17050, Q66H12, Q9QWR8
Gene Alias Acetylgalactosaminidase, alpha-N- (alpha-galactosidase B); alpha-galactosidase B; Alpha-N-acetylgalactosaminidase; D22S674; EC 3.2.1; EC 3.2.1.49; galactosidasealphaB; galactosidase-alphaB; GALB; N-acetyl galactosaminidase, alpha; N-acetylgalactosaminidase, alpha-; Naga
Gene Symbols NAGA
Host Species Rabbit
Immunogen Recombinant protein (or fragment).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17939, 315165, 4668
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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