Invitrogen™ NAGS Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA543666

Catalog No. PIPA543666

Description

Peptide sequence: YLDKFVVSSS RQGQGSGQML WECLRRDLQT LFWRSRVTNP INPWYFKHSD Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%.

NAGS is a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and, thereby, CPSI activity. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.

Specifications

• Antigen: NAGS
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NAGS
• Gene Alias: 1700120E20Rik; AGAS; Amino-acid acetyltransferase; amino-acid N-acetyltransferase; ARGA; LOW QUALITY PROTEIN: N-acetylglutamate synthase, mitochondrial; MGC133025; N-acetylglutamate synthase; N-acetylglutamate synthase conserved domain form; N-acetylglutamate synthase long form; N-acetylglutamate synthase short form; N-acetylglutamate synthase, conserved domain form; N-acetylglutamate synthase, mature form; N-acetylglutamate synthase, mitochondrial; Nags; NAGS-C; NAGS-M; RGD1565783
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 162417
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q8N159
• Gene Symbols: NAGS
• Immunogen: Synthetic peptide directed towards the C-terminal of human NAGS (aa 441-490).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov