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Invitrogen™ NAGS Polyclonal Antibody
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Catalog No. PIPA565010
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100 μL
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PIPA565010 100 μL
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Catalog No. PIPA565010 Supplier Invitrogen™ Supplier No. PA565010
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PTKIIFLNNTG GLRDSSHKVL SNVNLPADLD LVCNAEWVST KERQQMRLIV DVLSRLPHHS SAVITAASTL LTELFSNKGS GTLFKNAERM LRVRSLDKLD QGRLVDLV Highest antigen sequence identity to the following orthologs - mouse 87%, rat 90%.

NAGS is a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and, thereby, CPSI activity. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NAGS
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene NAGS
Gene Accession No. Q8N159
Gene Alias 1700120E20Rik; AGAS; Amino-acid acetyltransferase; amino-acid N-acetyltransferase; ARGA; LOW QUALITY PROTEIN: N-acetylglutamate synthase, mitochondrial; MGC133025; N-acetylglutamate synthase; N-acetylglutamate synthase conserved domain form; N-acetylglutamate synthase long form; N-acetylglutamate synthase short form; N-acetylglutamate synthase, conserved domain form; N-acetylglutamate synthase, mature form; N-acetylglutamate synthase, mitochondrial; Nags; NAGS-C; NAGS-M; RGD1565783
Gene Symbols NAGS
Host Species Rabbit
Immunogen Recombinant Human NAGS. Recombinant protein control fragment (Product #RP-105775).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 162417
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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