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Tocris Bioscience™ NAI

Catalog No. 700410
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70-041-0 10 mg
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Catalog No. 70-041-0 Supplier Tocris Bioscience™ Supplier No. 7004/10
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Description

Reagent for RNA SHAPE-MaP experiments in vivo; cell permeable

NAI is a reagent for RNA SHAPE-MaP experiments in live cells. Acylates the 2'-OH in RNA, labels single stranded or flexible regions more than folded regions (SHAPE methodology). Enables analysis of RNA secondary structures at single nucleotide resolution. Exhibits greater signals with lower background than 1M7 for in vivo measurement of the RNA structurome. Also more stable than 1M7 in water. β-mercaptoethanol terminates reaction. Cell permeable.

Specifications

Chemical Name or Material 1 H-Imidazol-1-yl(2-methyl-3-pyridinyl)methanone
CAS 1055970-47-2
Quantity 10 mg
Target DNA, RNA and Protein Synthesis Compounds
Molecular Formula C10H9N3O
Formula Weight 2424
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