Invitrogen™ NAIF1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA565903

Catalog No. PIPA565903

Description

Immunogen sequence: TVTLTQIPTET TYHTLEEGVV EYCTAEAPPP LPPETPVDMM AQHADTSVKP QALKSRIALN SAKLIQEQRV TNLHVKEIAQ HL Highest antigen sequence identity to the following orthologs - mouse 92%, rat 90%.

Human NAIF1 is located on chromosome 9q34.11 and encodes 327 amino acids with a homeodomain-like region and two nuclear localization signals at its N-terminal region. NAIF1 is conserved across diverse species, including human, mouse, crab-eating macaque, dog, chicken and frog, and shares no obvious homology to any known genes or proteins. NAIF1 was predominantly localized in the nucleus. Overexpression of NAIF1 inhibited cell growth and induced apoptosis. Furthermore, NAIF1 transfection caused both decreases in mitochondrial membrane potential and caspase-3 activation. In summary, NAIF1 is a nuclear protein that induces apoptosis when overexpressed.

Specifications

• Antigen: NAIF1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NAIF1
• Gene Alias: 2310007O20Rik; 4933440H19Rik; bA379C10.2; C9orf90; NAIF1; nuclear apoptosis inducing factor 1; nuclear apoptosis-inducing factor 1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 203245
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q69YI7
• Gene Symbols: NAIF1
• Immunogen: Recombinant Human NAIF1. Recombinant protein control fragment (Product #RP-106581).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG