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Invitrogen™ NAIF1 Polyclonal Antibody
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Catalog No. PIPA565903
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100 μL
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PIPA565903 100 μL
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Catalog No. PIPA565903 Supplier Invitrogen™ Supplier No. PA565903
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: TVTLTQIPTET TYHTLEEGVV EYCTAEAPPP LPPETPVDMM AQHADTSVKP QALKSRIALN SAKLIQEQRV TNLHVKEIAQ HL Highest antigen sequence identity to the following orthologs - mouse 92%, rat 90%.

Human NAIF1 is located on chromosome 9q34.11 and encodes 327 amino acids with a homeodomain-like region and two nuclear localization signals at its N-terminal region. NAIF1 is conserved across diverse species, including human, mouse, crab-eating macaque, dog, chicken and frog, and shares no obvious homology to any known genes or proteins. NAIF1 was predominantly localized in the nucleus. Overexpression of NAIF1 inhibited cell growth and induced apoptosis. Furthermore, NAIF1 transfection caused both decreases in mitochondrial membrane potential and caspase-3 activation. In summary, NAIF1 is a nuclear protein that induces apoptosis when overexpressed.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NAIF1
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene NAIF1
Gene Accession No. Q69YI7
Gene Alias 2310007O20Rik; 4933440H19Rik; bA379C10.2; C9orf90; NAIF1; nuclear apoptosis inducing factor 1; nuclear apoptosis-inducing factor 1
Gene Symbols NAIF1
Host Species Rabbit
Immunogen Recombinant Human NAIF1. Recombinant protein control fragment (Product #RP-106581).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 203245
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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