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Invitrogen™ NAIF1 Polyclonal Antibody
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Catalog No. PIPA590302
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100 μL
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PIPA590302 100 μL
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Catalog No. PIPA590302 Supplier Invitrogen™ Supplier No. PA590302
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MAVPAKKRKM NFSEREVEII VEELELKKHL LVNHFNAGVP LAAKSAAWHG ILRRVNAVAT CRRELPEVKK KWSDLKTEVR RKVAQVRAAV EGGEAPGPTE EDGAGGPGTG; Positive Samples: LO2, A375, 293T, OVCAR3, Mouse brain, Mouse liver, Rat brain, Rat liver; Cellular Location: Nucleus.

Human NAIF1 is located on chromosome 9q34.11 and encodes 327 amino acids with a homeodomain-like region and two nuclear localization signals at its N-terminal region. NAIF1 is conserved across diverse species, including human, mouse, crab-eating macaque, dog, chicken and frog, and shares no obvious homology to any known genes or proteins. NAIF1 was predominantly localized in the nucleus. Overexpression of NAIF1 inhibited cell growth and induced apoptosis. Furthermore, NAIF1 transfection caused both decreases in mitochondrial membrane potential and caspase-3 activation. In summary, NAIF1 is a nuclear protein that induces apoptosis when overexpressed.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NAIF1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.18 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene NAIF1
Gene Accession No. Q69YI7, Q6PFD7
Gene Alias 2310007O20Rik; 4933440H19Rik; bA379C10.2; C9orf90; NAIF1; nuclear apoptosis inducing factor 1; nuclear apoptosis-inducing factor 1
Gene Symbols NAIF1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human NAIF1 (NP_9310451).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 203245, 687739, 71254
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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