Invitrogen™ NAIF1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA590302

Catalog No. PIPA590302

Description

Immunogen sequence: MAVPAKKRKM NFSEREVEII VEELELKKHL LVNHFNAGVP LAAKSAAWHG ILRRVNAVAT CRRELPEVKK KWSDLKTEVR RKVAQVRAAV EGGEAPGPTE EDGAGGPGTG; Positive Samples: LO2, A375, 293T, OVCAR3, Mouse brain, Mouse liver, Rat brain, Rat liver; Cellular Location: Nucleus.

Human NAIF1 is located on chromosome 9q34.11 and encodes 327 amino acids with a homeodomain-like region and two nuclear localization signals at its N-terminal region. NAIF1 is conserved across diverse species, including human, mouse, crab-eating macaque, dog, chicken and frog, and shares no obvious homology to any known genes or proteins. NAIF1 was predominantly localized in the nucleus. Overexpression of NAIF1 inhibited cell growth and induced apoptosis. Furthermore, NAIF1 transfection caused both decreases in mitochondrial membrane potential and caspase-3 activation. In summary, NAIF1 is a nuclear protein that induces apoptosis when overexpressed.

Specifications

• Antigen: NAIF1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NAIF1
• Gene Alias: 2310007O20Rik; 4933440H19Rik; bA379C10.2; C9orf90; NAIF1; nuclear apoptosis inducing factor 1; nuclear apoptosis-inducing factor 1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 203245, 687739, 71254
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.18 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q69YI7, Q6PFD7
• Gene Symbols: NAIF1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human NAIF1 (NP_9310451).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov