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Invitrogen™ NAIP Polyclonal Antibody
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Catalog No. PIPA559978
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100 μL
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PIPA559978 100 μL
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Catalog No. PIPA559978 Supplier Invitrogen™ Supplier No. PA559978
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: KSGIQCFCCS LILFGAGLTR LPIEDHKRFH PDCGFLLNKD VGNIAKYDIR VKNLKSRLRG GKMRYQEEEA RLASFRNWPF YVQGISPCVL SEAGFVFTGK QD Highest antigen sequence identity to the following orthologs: Mouse - 70%, Rat - 66%.

Neuronal apoptosis inhibitor protein (NAIP) was the first human inhibitor of apoptosis protein (IAP) identified and was discovered by its association with the neurodegenerative disorder spinal muscular atrophy. Members of the IAP family contain one to three copies of an approximately 70 amino acid motif termed baculovirus IAP repeat (BIR); these BIRs promote protein-protein interactions with various caspases such as caspase-3, -7, and -9 as well as members of the TRAF family of signal molecules (reviewed in 3). Unlike other IAPs however, NAIP requires ATP to bind caspase-9 and is not inhibited by the IAP-inhibiting molecule Smac/DIABLO, suggesting that NAIP is unique among the IAPs in its regulation of its activity. Finally, although only one human NAIP protein has been identified, other shorter NAIP mRNA transcripts have been reported.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NAIP
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene NAIP
Gene Accession No. Q13075
Gene Alias AV364616; baculoviral IAP repeat-containing 1a; baculoviral IAP repeat-containing protein 1; Baculoviral IAP repeat-containing protein 1a; BIRC1; Birc1a; D13Lsd1; FLJ18088; FLJ42520; FLJ58811; Naip; Naip1; Naip-rs1; Neuronal apoptosis inhibitory protein; neuronal apoptosis inhibitory protein 1; NLR family apoptosis inhibitory protein; NLR family, apoptosis inhibitory protein; NLR family, apoptosis inhibitory protein 1; NLRB1; nucleotide-binding oligomerization domain, leucine rich repeat and BIR domain containing 1; psi neuronal apoptosis inhibitory protein; psiNAIP
Gene Symbols NAIP
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human NAIP. Recombinant protein control fragment (Product #RP-92089).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4671
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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