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Invitrogen™ Naja kaouthia Cobra Venom Factor Polyclonal Antibody
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Catalog No. PIPA5117705
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100 μg
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PIPA5117705 100 μg
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Catalog No. PIPA5117705 Supplier Invitrogen™ Supplier No. PA5117705
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Description

Rabbit Polyclonal Antibody

This antibody has been tested in direct-ELISA.

Complement-activating protein in cobra venom. It is a structural and functional analog of complement component C3b, the activated form of C3. It binds factor B (CFB), which is subsequently cleaved by factor D (CFD) to form the bimolecular complex CVF/Bb. CVF/Bb is a C3/C5 convertase that cleaves both complement components C3 and C5. Structurally, it resembles the C3b degradation product C3c, which is not able to form a C3/C5 convertase. Unlike C3b/Bb, CVF/Bb is a stable complex and completely resistant to the actions of complement regulatory factors H (CFH) and I (CFI). Therefore, CVF continuously activates complement resulting in the depletion of complement activity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Naja kaouthia Cobra Venom Factor
Applications Western Blot
Classification Polyclonal
Concentration 5 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Alias CVF
Host Species Rabbit
Immunogen Recombinant Naja kaouthia Cobra venom factor protein (733-984aa).
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Reptile
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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