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Invitrogen™ NALP1 Polyclonal Antibody
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Catalog No. PIPA5100640
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PIPA5100640 100 μL
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Catalog No. PIPA5100640 Supplier Invitrogen™ Supplier No. PA5100640
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total NLRP1.

NALP1 is a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NALP1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene NLRP1
Gene Accession No. Q9C000
Gene Alias CARD7; caspase recruitment domain protein; caspase recruitment domain protein 7; caspase recruitment domain-containing protein 7; CIDED; CLR17.1; death effector filament-forming Ced-4-like apoptosis protein; DEFCAP; DEFCAP-L/S; DKFZp586O1822; Gm14; Gm15; KIAA0926; NAC; nacht; NACHT, leucine rich repeat and PYD (pyrin domain) containing 1; NACHT, leucine rich repeat and PYD containing 1; NACHT, LRR and PYD containing protein 1; NACHT, LRR and PYD domains-containing protein 1; NACHT, LRR and PYD domains-containing protein 1a; NACHT/LRR/pyrin domain-containing protein 1; Nalp1; Nalp1a; NLR family protein 1; NLR family pyrin domain containing 1; NLR family, pyrin domain containing 1; NLR family, pyrin domain containing 1A; Nlrp1; Nlrp1a; Nucleotide-binding domain and caspase recruitment domain; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 1; PP1044; resistant anthrax lethal toxin; SLEV1; VAMAS1
Gene Symbols NLRP1
Host Species Rabbit
Immunogen A synthesized peptide derived from human NLRP1(Accession Q9C000), corresponding to amino acid residues K229-T279.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22861
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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