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Invitrogen™ NALP11 Polyclonal Antibody
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Catalog No. PIPA588368
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100 μL
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PIPA588368 100 μL
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Catalog No. PIPA588368 Supplier Invitrogen™ Supplier No. PA588368
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: VGFTEADVSV LQAANILLPS NTHKDRYKFI HLNVQEFCTA IAFLMAVPNY LIPSGSREYK EKREQYSDFN QVFTFIFGLL NANRRKILET SFGYQLPMVD SFKWYSVGYM KHLDRDPEKL THHMPLFYCL YENREEEFVK TIVDALMEVT VYLQSDKDMM VSLYCLDYCC HLRTLKLSVQ R; Positive Samples: 293T.

NALP11 is a 1033 amino acid containing cytoplasmic protein belonging to the NLRP family with a DAPIN domain, six LRR (leucine-rich) repeats and a NACHT domain. Reports suggest that it is a short NALP involved in inflammation potential. NALP proteinsare implicated in the activation of proinflammatory caspases (e.g., CASP1) via their involvement in multiprotein complexes called inflammasomes. The DAPIN domain is necessary and sufficient for suppression of NF-kappa B activation induced by TNF and for inducing IL-1B secretion in collaboration with Caspase-1. It is involved in interaction with PYCARD.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NALP11
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.26 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene NLRP11
Gene Accession No. P59045
Gene Alias CLR19.6; NACHT, leucine rich repeat and PYD containing 11; NACHT, LRR and PYD domains-containing protein 11; NALP11; NLR family pyrin domain containing 11; NLR family, pyrin domain containing 11; NLRP11; NOD17; Nucleotide-binding oligomerization domain protein 17; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 11; PAAD- and NACHT-containing protein 10B; PAAD-and NACHT domain-containing protein 10; PAN10; PYPAF6; PYPAF7; PYRIN-containing APAF1-like protein 6
Gene Symbols NLRP11
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 420-600 of human NLRP11 (NP_6594442).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 204801
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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