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Invitrogen™ NALP5 Polyclonal Antibody
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Catalog No. PIPA585953
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100 μL
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PIPA585953 100 μL
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Catalog No. PIPA585953 Supplier Invitrogen™ Supplier No. PA585953
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Description

Rabbit Polyclonal Antibody

NALP5 Polyclonal Antibody for ICC/IF

NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP5, also known as MATER, is a maternal gene required for early embryonic development in mice. Increased NALP5 expression was observed in two neuronal injury models, and transient expression of recombinant NALP5 in neurons induced caspase-3 activation and apoptosis, suggesting that NALP5 also plays a role in caspase activation and apoptosis in injured neurons, and may thus represent a novel target for therapeutic treatment in neurodegenerative disorders.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NALP5
Applications Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% Glycerol, 0.2% BSA and 0.05% sodium azide; pH 7.4
Gene NLRP5
Gene Accession No. P59047, Q9R1M5
Gene Alias CLR19.8; MATER; Mater protein; Mater protein homolog; maternal antigen that embryos require; NACHT, leucine rich repeat and PYD containing 5; NACHT, LRR and PYD domains-containing protein 5; Nalp5; NLR family pyrin domain containing 5; NLR family, pyrin domain containing 5; NLRP5; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 5; Ooplasm-specific protein 1; OP1; PAN11; PYPAF8
Gene Symbols NLRP5
Host Species Rabbit
Immunogen Synthetic peptide within mouse MATER aa 1,114-1,163.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 126206, 23968
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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