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NALP6 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501980877
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50-198-0877 100 μL
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Catalog No. 50-198-0877 Supplier Bioss Supplier No. BS10440R
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Description

Rabbit Polyclonal Antibody

NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP6, also known as PYPAF5, is highly expressed in granulocytes and T cells and co-localizes with the PYRIN-CARD protein ASC. Co-expression of NALP6 with ASC results in a synergistic activation of NF-kappa-B and activated caspase-1-dependent cytokine processing, suggesting that NALP6 functions in immune cells to coordinate the transduction of pro-inflammatory signals.

Specifications

Antigen NALP6
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene NLRP6
Gene Accession No. P59044
Gene Alias AI504961; Angiotensin II/vasopressin receptor; AVR; CLR11.4; NACHT, leucine rich repeat and PYD containing 6; NACHT, LRR and PYD domains-containing protein 6; NACHT/LRR/pyrin domain-containing protein 6; Nalp6; Navr; NAVR/AVR; NLR family pyrin domain containing 6; NLR family, pyrin domain containing 6; Nlrp6; Non-angiotensin-vasopressin receptor; Non-AVR; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 6; PAN3; Pypaf5; PYRIN-containing APAF1-like protein 5; PYRIN-containing APAF1-like protein 5-like
Gene Symbols NLRP6
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human NALP6.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 171389
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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