Invitrogen™ NALP8 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA563381

Catalog No. PIPA563381

Description

Immunogen sequence: EDLNVGETQV NLEEGESGKI RRYKSNVMEK FFPIWDITTW PGNQRDFFYQ GVHRHEEYLP CLLLPKRPQG RQPKTVA Highest antigen sequence identity to the following orthologs: Mouse - 25%, Rat - 26%.

NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP8 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It maps to chromosome 19q13.42 and is thought to be expressed in testis and ovary, suggesting that NALP8 may be involved in reproduction. Surprisingly, NALP8 seems to be universal in mammals except for rodents, suggesting that the gene may have been lost during evolution.

Specifications

• Antigen: NALP8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NLRP8
• Gene Alias: CLR19.2; NACHT, leucine rich repeat and PYD containing 8; NACHT, LRR and PYD containing protein 8; NACHT, LRR and PYD domains-containing protein 8; NALP8; NLR family pyrin domain containing 8; NLR family, pyrin domain containing 8; NLRP8; NOD16; Nucleotide-binding oligomerization domain protein 16; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 8; PAN4; PYRIN and NACHT-containing protein 4
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 126205
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q86W28
• Gene Symbols: NLRP8
• Immunogen: Recombinant protein corresponding to Human NALP8. Recombinant protein control fragment (Product #RP-101527).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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