Invitrogen™ NANS Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531140

Catalog No. PIPA531140

Description

Recommended positive controls: HepG2. Predicted reactivity: Mouse (97%), Rat (97%), Xenopus laevis (84%), Pig (98%), Chicken (93%), Bovine (97%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively; however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant.

Specifications

• Antigen: NANS
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NANS
• Gene Alias: 4632418E04Rik; BB056474; epididymis secretory protein Li 100; HEL-S-100; N-acetylneuraminate synthase; N-acetylneuraminate-9-phosphate synthase; N-acetylneuraminic acid 9-phosphate synthetase; N-acetylneuraminic acid phosphate synthase; N-acetylneuraminic acid synthase; N-acetylneuraminic acid synthase (sialic acid synthase); Nans; RP11-404F11.3; SAS; SEMDG; sialic acid phosphate synthase; sialic acid synthase
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 54187
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q9NR45
• Gene Symbols: NANS
• Immunogen: Recombinant fragment corresponding to a region within amino acids 11 and 271 of Human NANS.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov