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Invitrogen™ NANS Polyclonal Antibody
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Catalog No. PIPA596300
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PIPA596300 100 μL
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Catalog No. PIPA596300 Supplier Invitrogen™ Supplier No. PA596300
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Rabbit Polyclonal Antibody

Immunogen sequence: AELVRSVRLV ERALGSPTKQ LLPCEMACNE KLGKSVVAKV KIPEGTILTM DMLTVKVGEP KGYPPEDIFN LVGKKVLVTV EEDDTIMEEL VDNHGKKIKS; Positive Samples: A-549, OVCAR3, A-431.

This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively; however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NANS
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.41 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene NANS
Gene Accession No. Q9NR45
Gene Alias 4632418E04Rik; BB056474; epididymis secretory protein Li 100; HEL-S-100; N-acetylneuraminate synthase; N-acetylneuraminate-9-phosphate synthase; N-acetylneuraminic acid 9-phosphate synthetase; N-acetylneuraminic acid phosphate synthase; N-acetylneuraminic acid synthase; N-acetylneuraminic acid synthase (sialic acid synthase); Nans; RP11-404F11.3; SAS; SEMDG; sialic acid phosphate synthase; sialic acid synthase
Gene Symbols NANS
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 260-359 of human NANS (NP_0618192).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54187
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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