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Tocris Bioscience™ Napabucasin
GREENER_CHOICE

Catalog No. 552210
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

STAT3 inhibitor; also blocks cancer stem cell self-renewal

Napabucasin is a STAT3 inhibitor. Blocks spherogenesis of cancer stem cells (CSC), but not hematopoietic stem cells. Inhibits PaCa-2 xenograft tumor growth in mice, even after cessation of treatment, and decreases population of CSCs in PaCa-2 tumors from treated mice. Also blocks spleen and liver metastases of colon cancer cells in a mouse model.

Specifications

Chemical Name or Material 2-Acetylnaphtho[2,3-b]furan-4,9-dione
CAS 83280-65-3
Quantity 10 mg
Target STAT Inhibitors
Molecular Formula C14H8O4
Formula Weight 240.21
Purity >98%
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