Invitrogen™ NAPE PLD Monoclonal Antibody (OTI5F7)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA525761

Catalog No. PIMA525761

Description

NAPE PLD Monoclonal Antibody for Western Blot, ICC/IF, IHC (P), Flow

N-Acylphosphatidylethanolamine (NAPE)-hydrolyzing phospholipase D (NAPE-PLD) is a membrane-bound enzyme which releases the endocannabinoid anandamide and other bioactive N-acylethanolamines from their corresponding NAPEs in animal tissues. NAPE-PLD has been shown to be expressed by specific populations of neurons in the brain and targeted to axonal processes. Recent studies have suggested that NAEs generated by NAPE-PLD in axons may act as anterograde synaptic signaling molecules that regulate the activity of postsynaptic neurons. NAPE-PLD has also been shown to catalyze the hydrolysis of NAPE to generate OEA (oleoylethanolamide), a natural lipid amide that inhibits food intake in free-feeding rodents by prolonging latency to feed and postmeal interval.

Specifications

• Antigen: NAPE PLD
• Classification: Monoclonal
• Concentration: 0.71 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q6IQ20
• Gene Symbols: NAPEPLD
• Immunogen: Full length human recombinant protein of NAPEPLD produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: OTI5F7
• Conjugate: Unconjugated
• Gene: NAPEPLD
• Gene Alias: A530089G06; C7orf18; DKFZp781D1098; FMP30; Mbldc1; Metallo-beta-lactamase domain containing 1; N-acyl phosphatidylethanolamine phospholipase D; N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D; NAPE-hydrolyzing phospholipase D; NAPEPLD; NAPE-PLD
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 222236
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid