Invitrogen™ NAPE PLD Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA554092

Catalog No. PIPA554092

Description

Immunogen sequence: MKYQHVDPEE AVRIHTDVQT KKSMAIHWGT FALANEHYLE PPVKLNEALE RYGLNAEDFF VLKHGESRYL NNDDE Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 85%.

N-Acylphosphatidylethanolamine (NAPE)-hydrolyzing phospholipase D (NAPE-PLD) is a membrane-bound enzyme which releases the endocannabinoid anandamide and other bioactive N-acylethanolamines from their corresponding NAPEs in animal tissues. NAPE-PLD has been shown to be expressed by specific populations of neurons in the brain and targeted to axonal processes. Recent studies have suggested that NAEs generated by NAPE-PLD in axons may act as anterograde synaptic signaling molecules that regulate the activity of postsynaptic neurons. NAPE-PLD has also been shown to catalyze the hydrolysis of NAPE to generate OEA (oleoylethanolamide), a natural lipid amide that inhibits food intake in free-feeding rodents by prolonging latency to feed and postmeal interval.

Specifications

• Antigen: NAPE PLD
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NAPEPLD
• Gene Alias: A530089G06; C7orf18; DKFZp781D1098; FMP30; Mbldc1; Metallo-beta-lactamase domain containing 1; N-acyl phosphatidylethanolamine phospholipase D; N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D; NAPE-hydrolyzing phospholipase D; NAPEPLD; NAPE-PLD
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 222236
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q6IQ20
• Gene Symbols: NAPEPLD
• Immunogen: Recombinant protein corresponding to Human NAPEPLD. Recombinant protein control fragment (Product #RP-92784).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG