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Invitrogen™ NAPE PLD Polyclonal Antibody
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Catalog No. PIPA5115616
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PIPA5115616 100 μL
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Catalog No. PIPA5115616 Supplier Invitrogen™ Supplier No. PA5115616
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total NAPE-PLD.

N-Acylphosphatidylethanolamine (NAPE)-hydrolyzing phospholipase D (NAPE-PLD) is a membrane-bound enzyme which releases the endocannabinoid anandamide and other bioactive N-acylethanolamines from their corresponding NAPEs in animal tissues. NAPE-PLD has been shown to be expressed by specific populations of neurons in the brain and targeted to axonal processes. Recent studies have suggested that NAEs generated by NAPE-PLD in axons may act as anterograde synaptic signaling molecules that regulate the activity of postsynaptic neurons. NAPE-PLD has also been shown to catalyze the hydrolysis of NAPE to generate OEA (oleoylethanolamide), a natural lipid amide that inhibits food intake in free-feeding rodents by prolonging latency to feed and postmeal interval.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NAPE PLD
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene NAPEPLD
Gene Accession No. Q6IQ20, Q769K2, Q8BH82
Gene Alias A530089G06; C7orf18; DKFZp781D1098; FMP30; Mbldc1; Metallo-beta-lactamase domain containing 1; N-acyl phosphatidylethanolamine phospholipase D; N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D; NAPE-hydrolyzing phospholipase D; NAPEPLD; NAPE-PLD
Gene Symbols NAPEPLD
Host Species Rabbit
Immunogen A synthesized peptide derived from human NAPEPLD(Accession Q6IQ20), corresponding to amino acid residues L130-A180.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 222236, 242864, 296757
Target Species Human, Mouse, Rat, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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