NAPEPLD Monoclonal Antibody (OTI1H4), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA503892

Catalog No. 50-167-4673

Description

N-Acylphosphatidylethanolamine (NAPE)-hydrolyzing phospholipase D (NAPE-PLD) is a membrane-bound enzyme which releases the endocannabinoid adamide and other bioactive N-acylethanolamines from their corresponding NAPEs in animal tissues. NAPE-PLD has been shown to be expressed by specific populations of neurons in the brain and targeted to axonal processes. Recent studies have suggested that NAEs generated by NAPE-PLD in axons may act as anterograde synaptic signaling molecules that regulate the activity of postsynaptic neurons. NAPE-PLD has also been shown to catalyze the hydrolysis of NAPE to generate OEA (oleoylethanolamide), a natural lipid amide that inhibits food intake in free-feeding rodents by prolonging latency to feed and postmeal interval.

Specifications

• Antigen: NAPEPLD
• Classification: Monoclonal
• Concentration: 0.94 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q6IQ20
• Gene Symbols: NAPEPLD
• Immunogen: Full length human recombit protein of human NAPEPLD produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Clone: OTI1H4
• Conjugate: Unconjugated
• Gene: NAPEPLD
• Gene Alias: C7orf18, FMP30, NAPE-PLD
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 222236
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid