Invitrogen™ NAPRT1 Monoclonal Antibody (CL0366)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA524602

Catalog No. PIMA524602

Description

Immunogen sequence: LLDTYSVWRS GLPNFLAVAL ALGELGYRAV GVRLDSGDLL QQAQEIRKVF RAAAAQFQVP WLESVLIVVS NNIDEEALAR LAQEGSEVNV IGIGTSV Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 82%. Binds to an epitope located within the peptide sequence IRKVFRAAAA as determined by overlapping synthetic peptides.

Nicotinic acid (NA; niacin) is converted by nicotinic acid phosphoribosyltransferase (NAPRT; EC 2.4.2.11) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD), which serves as a coenzyme in cellular redox reactions and is an essential component of a variety of processes in cellular metabolism including response to stress (Hara et al., 2007).

Specifications

• Antigen: NAPRT1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q6XQN6
• Gene Symbols: NAPRT
• Immunogen: Recombinant protein corresponding to Human NAPRT1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: CL0366
• Conjugate: Unconjugated
• Gene: NAPRT
• Gene Alias: 9130210N20Rik; FHA-HIT-interacting protein; FHIP; hypothetical protein MGC77870; Naprt; Naprt1; NAPRTase; Nicotinate phosphoribosyltransferase; nicotinate phosphoribosyltransferase domain containing 1; nicotinate phosphoribosyltransferase domain-containing protein 1; nicotinate phosphoribosyltransferase; LOW QUALITY PROTEIN: nicotinate phosphoribosyltransferase; nicotinate phosphoribosyltransferase-like protein; nicotinic acid phosphoribosyltransferase; PP3856; zgc:77870
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 93100
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid