Invitrogen™ NAPSA Monoclonal Antibody (A9B12)

Catalog No.	Quantity
FEMA550614	100 μL

Catalog No. FEMA550614 Supplier Invitrogen™ Supplier No. MA550614

Description

Mouse Monoclonal Antibody

Positive control: Human kidney tissue, human lung carcinoma tissue. Predicted band size: 45 kDa Subcellular Location: Secreted.

Napsin 1 is an aspartic protease that is generally expressed in the lung, but also present in kidney and in metastatic carcinomas throughout the body. Napsin 1 processes surfactant protein B in healthy pulmonary and renal tissues, but is abnormally regulated when carcinogenesis occurs. Thus, many researchers have found napsin evaluation to be useful in identifying several cancers, and differentiating primary tumors from metastases. When combined with thyroid transcription factor analysis, napsin can be used as a specific biomarker for differentiation of carcinoma types. Napsin has also been associated with pulmonary alveolar proteinosis as well as in protein catabolism in renal tubules.

Specifications

• Antigen: NAPSA
• Applications: Immunohistochemistry (Paraffin)
• Classification: Monoclonal
• Clone: A9B12
• Concentration: 2 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene: NAPSA
• Gene Accession No.: O96009
• Gene Alias: asp 4; ASP4; Aspartyl protease 4; KAP; Kdap; KDAP-1; kidney-derived aspartic protease-like protein; Nap; NAP1; NAPA; Napsa; napsin A aspartic peptidase; napsin-1; Napsin-A; pronapsin; pronapsin A; SNAPA; TA01/TA02
• Gene Symbols: NAPSA
• Host Species: Mouse
• Immunogen: Recombinant protein within human NAPSIN A aa 51-200/420.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 9476
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2a