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Invitrogen™ NAPSA Monoclonal Antibody (CL12954)
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Catalog No. PIMA546528
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100 μL
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Catalog No. Quantity
PIMA546528 100 μL
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Catalog No. PIMA546528 Supplier Invitrogen™ Supplier No. MA546528
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Description

Mouse Monoclonal Antibody

Highest antigen sequence indentity to the following orthologs: Rat - 78%, Mouse - 76%.

Napsin 1 is an aspartic protease that is generally expressed in the lung, but also present in kidney and in metastatic carcinomas throughout the body. Napsin 1 processes surfactant protein B in healthy pulmonary and renal tissues, but is abnormally regulated when carcinogenesis occurs. Thus, many researchers have found napsin evaluation to be useful in identifying several cancers, and differentiating primary tumors from metastases. When combined with thyroid transcription factor analysis, napsin can be used as a specific biomarker for differentiation of carcinoma types. Napsin has also been associated with pulmonary alveolar proteinosis as well as in protein catabolism in renal tubules.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NAPSA
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone CL12954
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene NAPSA
Gene Accession No. O96009
Gene Alias asp 4; ASP4; Aspartyl protease 4; KAP; Kdap; KDAP-1; kidney-derived aspartic protease-like protein; Nap; NAP1; NAPA; Napsa; napsin A aspartic peptidase; napsin-1; Napsin-A; pronapsin; pronapsin A; SNAPA; TA01/TA02
Gene Symbols NAPSA
Host Species Mouse
Immunogen Synthetic Peptide.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9476
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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