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NAT1 Mouse anti-Human, Clone: OTI7G6, lyophilized, TrueMAB™

Mouse Monoclonal Antibody
Supplier: OriGene CF810662

Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
Arylamine N-acetyltransferases (NAT-1 and NAT-2) catalyze N- or O-acetylation of heterocyclic and arylamine substrates in the detoxification of a wide array of drugs. Certain alleles causing high N-acetyltransferase activity have been associated with colon and urinary bladder cancers, as NATs also bioactivate several known carcinogens. Both NAT-1 and NAT-2 are cytoplasmic proteins and play an active role in the detoxification of many arylamine and hydrazine drugs. N-acetylation polymorphism is determined by the level of NAT activity in liver tissues, and has been linked to the action and toxicity of drugs that contain amines. Human NAT-1 is the functional homolog of rodent NAT-2, while human NAT-2 is the functional homolog of rodent NAT-1.Specifications
NAT1 | |
Monoclonal | |
Unconjugated | |
NAT1 | |
AAC1, MNAT, NAT-1, NATI | |
Mouse | |
Affinity Chromatography | |
RUO | |
9 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Western Blot | |
OTI7G6 | |
PBS with 8% trehalose and no preservative; pH 7.3 | |
P18440 | |
NAT1 | |
Full length human recombit protein of human NAT1 produced in E.coli. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG1 |
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