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NAT1 Mouse anti-Human, Clone: OTI7G6, lyophilized, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene CF810662

Encompass_Preferred

Catalog No. 50-167-0235


May include imposed supplier surcharges.
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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Arylamine N-acetyltransferases (NAT-1 and NAT-2) catalyze N- or O-acetylation of heterocyclic and arylamine substrates in the detoxification of a wide array of drugs. Certain alleles causing high N-acetyltransferase activity have been associated with colon and urinary bladder cancers, as NATs also bioactivate several known carcinogens. Both NAT-1 and NAT-2 are cytoplasmic proteins and play an active role in the detoxification of many arylamine and hydrazine drugs. N-acetylation polymorphism is determined by the level of NAT activity in liver tissues, and has been linked to the action and toxicity of drugs that contain amines. Human NAT-1 is the functional homolog of rodent NAT-2, while human NAT-2 is the functional homolog of rodent NAT-1.
Specifications

Specifications

NAT1
Monoclonal
Unconjugated
NAT1
AAC1, MNAT, NAT-1, NATI
Mouse
Affinity Chromatography
RUO
9
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
Western Blot
OTI7G6
PBS with 8% trehalose and no preservative; pH 7.3
P18440
NAT1
Full length human recombit protein of human NAT1 produced in E.coli.
100 μg
Primary
Human
Antibody
IgG1
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