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Tocris Bioscience™ NAV 2729

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Quantity:
10 mg
50 mg
Description
NAV 2729 is a selective ARF6 inhibitor (IC50 = 1.0 μM). Selective for ARF6 over other ARF family members and small GTPases. Inhibits ARF6 activation in uveal melanoma cells in vitro and blocks downstream signaling pathways of oncogenic GNAQ. Reduces tumorigenesis in mouse model of uveal melanoma.
Specifications
Specifications
CAS | 419547-11-8 |
Quantity | 50 mg |
Solubility | Soluble to 100mM in DMSO |
Molecular Formula | C25H17ClN4O3 |
Formula Weight | 456.88g/mol |
Color | Yellow |
Product Type | Inhibitor |
For Research Use Only
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