Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. Tocris Bioscience™ NAV 2729

Tocris Bioscience™ NAV 2729
GREENER_CHOICE

Catalog No. 598650
Change view
Click to view available options
Quantity:
10 mg
50 mg
2 product options available for selection
Product selection table with 2 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
59-865-0 50 mg
59-861-0 10 mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 2 options available.
2 options
This item is not returnable. View return policy
Catalog No. 59-865-0 Supplier Tocris Bioscience™ Supplier No. 5986/50
Only null left
Add to Cart
Add to Cart
This item is not returnable. View return policy

Description

Selective ARF6 inhibitor

NAV 2729 is a selective ARF6 inhibitor (IC50 = 1.0 μM). Selective for ARF6 over other ARF family members and small GTPases. Inhibits ARF6 activation in uveal melanoma cells in vitro and blocks downstream signaling pathways of oncogenic GNAQ. Reduces tumorigenesis in mouse model of uveal melanoma.

Specifications

CAS 419547-11-8
Quantity 50 mg
Solubility Soluble to 100mM in DMSO
Molecular Formula C25H17ClN4O3
Formula Weight 456.88g/mol
Color Yellow
Product Type Inhibitor

For Research Use Only

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.