Invitrogen™ Ganglioside GD2 (Naxitamab Biosimilar) Recombinant Human Monoclonal Antibody

Catalog No.	Quantity
PIMA542231	100 μg

Catalog No. PIMA542231 Supplier Invitrogen™ Supplier No. MA542231

Description

Human Recombinant Monoclonal Antibody

Endotoxin level <0.01EU/μg by LAL method Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt. This product is a Humanized mouse antibody.

Ganglioside GD2 is a disialoganglioside (glycosphingolipid) expressed on the outer surface of the plasma membrane. It is highly expressed in tumors of neuroectodermal origin, including neuroblastoma, melanoma, osteosarcoma, and small cell lung cancer, while showing limited distribution in normal tissues, primarily in peripheral nerves and the central nervous system. GD2 plays roles in cell adhesion, migration, and signal transduction. Because of its high tumor expression and restricted normal tissue distribution, GD2 is an established target for antibody-based immunotherapies, particularly in high-risk neuroblastoma.

Specifications

• Antigen: Ganglioside GD2 (Naxitamab Biosimilar)
• Applications: ELISA, SDS-Page
• Classification: Recombinant Monoclonal
• Concentration: 3.45 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with no preservative; pH 7.4
• Gene Alias: Hu3F8
• Host Species: Human
• Immunogen: Human Ganglioside GD2.
• Purification Method: Protein A/G
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1 κ
• Target Molecule: Chemical