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Invitrogen™ NBL1 Polyclonal Antibody
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Catalog No. PIPA547972
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100 μg
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PIPA547972 100 μg
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Catalog No. PIPA547972 Supplier Invitrogen™ Supplier No. PA547972
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Description

Goat Polyclonal Antibody

In direct ELISAs, approximately 25% cross-reactivity with recombinant mouse (rm) DAN is observed and less than 1% cross-reactivity with recombinant chicken Caronte, rmGremlin, and recombinant human Cerberus 1 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

This gene product is the founding member of the evolutionarily conserved CAN family of proteins, which contain a domain resembling the CTCK motif found in a number of signaling molecules. These proteins are secreted, and act as BMP antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NBL1
Applications Immunohistochemistry, Neutralization, Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene Nbl1
Gene Accession No. P41271
Gene Alias D1S1733E; D4H1S1733E; DAN; DAN domain family member 1; Dana; DAND1; differential screening-selected gene aberrant in neuroblastoma; N03; NB; Nbl1; neuroblastoma 1, DAN family BMP antagonist; neuroblastoma candidate region, suppression of tumorigenicity 1; neuroblastoma suppressor of tumorigenicity 1; neuroblastoma, suppression of tumorigenicity 1; Neuroblastoma, suppression of tumorigenicity 1 (DNA segment human D1S1733E); NO3; Protein N03; Zinc finger protein DAN
Gene Symbols Nbl1
Host Species Goat
Immunogen Mouse myeloma cell line NS0-derived recombinant human DAN Ala17-Asp180 (Ala36Arg).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4681
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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