NBN Monoclonal Antibody (OTI1G1), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA801220

Catalog No. 50-167-8736

Description

The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex. This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity, thus revealing a direct molecular link between double-strand break repair and cell cycle checkpoint functions.

Specifications

• Antigen: NBN
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: O60934
• Gene Symbols: NBN
• Immunogen: Human recombit protein fragment corresponding to amino acids 461-754 of human NBN produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI1G1
• Conjugate: Unconjugated
• Gene: NBN
• Gene Alias: AT-V1, AT-V2, ATV, NBS, NBS1, P95
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4683
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid