NBN Mouse anti-Human, Clone: UMAB100, lyophilized, UltraMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene UM800030CF

Catalog No. 50-168-5191

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex. This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity, thus revealing a direct molecular link between double-strand break repair and cell cycle checkpoint functions.

Specifications

• Antigen: NBN
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: NBN
• Gene Alias: AT-V1, AT-V2, ATV, NBS, NBS1, P95
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4683
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Peptide Array
• Clone: UMAB100
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: O60934
• Gene Symbols: NBN
• Immunogen: Human recombit protein fragment corresponding to amino acids 183-460 of human NBN produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1