Invitrogen™ NBS1 Monoclonal Antibody (1D7)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA123265

Catalog No. MA123265

Description

Predicted molecular weight 91 kDa. Positive control: MCF7, HeLa (NE), Raji.

The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex. This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity, thus revealing a direct molecular link between double-strand break repair and cell cycle checkpoint functions.

Specifications

• Antigen: NBS1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and no preservative; pH 7
• Gene Accession No.: O60934, Q9JIL9, Q9R207
• Gene Symbols: NBN
• Immunogen: The complete coding region of the human p95/NBS1 expressed in E. coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunoprecipitation, Western Blot, Immunocytochemistry
• Clone: 1D7
• Conjugate: Unconjugated
• Gene: NBN
• Gene Alias: AT V1; AT V2; ATV; AT-V1; AT-V2; Cell cycle regulatory protein p95; FLJ10155; I79_012607; MGC87362; Nbn; NBS; NBS1; nibrin; Nijmegen breakage syndrome 1 (nibrin); Nijmegen breakage syndrome protein 1; Nijmegen breakage syndrome protein 1 homolog; OTTHUMP00000204088; P95; p95 protein of the MRE11/RAD50 complex; p95-NBS1
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 27354, 4683, 85482
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid