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Invitrogen™ NBS1 Monoclonal Antibody (7E4A2)
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Catalog No. PIMA538579
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100 μg
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Catalog No. Quantity
PIMA538579 100 μg
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Catalog No. PIMA538579 Supplier Invitrogen™ Supplier No. MA538579
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Description

Mouse Monoclonal Antibody

This antibody has been tested in indirect ELISA.

The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex. This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity, thus revealing a direct molecular link between double-strand break repair and cell cycle checkpoint functions.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NBS1
Applications ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 7E4A2
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene NBN
Gene Accession No. O60934, Q9JIL9
Gene Alias AT V1; AT V2; ATV; AT-V1; AT-V2; Cell cycle regulatory protein p95; FLJ10155; I79_012607; MGC87362; Nbn; NBS; NBS1; nibrin; Nijmegen breakage syndrome 1 (nibrin); Nijmegen breakage syndrome protein 1; Nijmegen breakage syndrome protein 1 homolog; OTTHUMP00000204088; P95; p95 protein of the MRE11/RAD50 complex; p95-NBS1
Gene Symbols NBN
Host Species Mouse
Immunogen Purified recombinant fragment of human NBN (aa: 467-615) expressed in E. Coli.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4683, 85482
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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