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Invitrogen™ NBS1 Recombinant Rabbit Monoclonal Antibody (SC05-68)
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Catalog No. PIMA542436
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100 μL
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PIMA542436 100 μL
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Catalog No. PIMA542436 Supplier Invitrogen™ Supplier No. MA542436
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Control: Human lung tissue lysates, Hela, A431. Subcellular Location: Nucleus, Chromosome.

The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex. This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity, thus revealing a direct molecular link between double-strand break repair and cell cycle checkpoint functions.
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Specifications

Antigen NBS1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone SC05-68
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 40% glycerol, 0.05% BSA and 0.05% sodium azide; pH 7.4
Gene NBN
Gene Accession No. O60934, Q9JIL9, Q9R207
Gene Alias AT V1; AT V2; ATV; AT-V1; AT-V2; Cell cycle regulatory protein p95; FLJ10155; I79_012607; MGC87362; Nbn; NBS; NBS1; nibrin; Nijmegen breakage syndrome 1 (nibrin); Nijmegen breakage syndrome protein 1; Nijmegen breakage syndrome protein 1 homolog; OTTHUMP00000204088; P95; p95 protein of the MRE11/RAD50 complex; p95-NBS1
Gene Symbols NBN
Host Species Rabbit
Immunogen Synthetic peptide within human p95 NBS1 aa 680-730.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27354, 4683, 85482
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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