Invitrogen™ NCALD Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531832

Catalog No. PIPA531832

Description

Recommended positive controls: NT2D1, PC-3, U87-MG, SK-N-SH. Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (98%), Pig (100%), Chicken (99%), Rhesus Monkey (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined.

Specifications

• Antigen: NCALD
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NCALD
• Gene Alias: AI848120; D030020D09Rik; D15Ertd412e; EGK_19177; NCALD; neurocalcin delta; neurocalcin-delta
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 52589, 553106, 83988
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P61601, Q5PQN0, Q91X97
• Gene Symbols: NCALD
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 191 of Human Neurocalcin delta.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov