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Invitrogen™ NCALD Polyclonal Antibody
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Catalog No. PIPA5121165
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100 μL
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PIPA5121165 100 μL
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Catalog No. PIPA5121165 Supplier Invitrogen™ Supplier No. PA5121165
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Description

Rabbit Polyclonal Antibody

Positive test controls include: A-549, THP-1, BT-474, Mouse brain, Mouse liver, Mouse lung, Mouse spinal cord, Rat brain. Immunogen sequence: MGKQNSKLRP EVMQDLLEST DFTEHEIQEW YKGFLRDCPS GHLSMEEFKK IYGNFFPYGD ASKFAEHVFR TFDANGDGTI DFREFIIALS VTSRGKLEQK LKWAFSMYDL DGNGYISKAE MLEIVQAIYK MVSSVMKMPE DESTPEKRTE KIFRQMDTNR DGKLSLEEFI RGAKSDPSIV RLLQCDPSSA GQF.

This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NCALD
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 3.59 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene NCALD
Gene Accession No. P61601, Q5PQN0, Q91X97
Gene Alias AI848120; D030020D09Rik; D15Ertd412e; EGK_19177; NCALD; neurocalcin delta; neurocalcin-delta
Gene Symbols NCALD
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-193 of human NCALD (NP_114430.2).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 52589, 553106, 83988
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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